Test ID SPASU Arsenic Speciation, 24 Hour, Urine
Specimen Required
Patient Preparation:
1. Patient should not eat seafood for a 48-hour period prior to start of collection.
2. High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine collection container
Submission Container/Tube: Plastic, 10-mL tube or a clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate urine specimen within 4 hours of completion of 24-hour collection
3. See Metals Analysis Specimen Collection and Transport for complete instructions.
Additional Information: For multiple collections see Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens
Useful For
Diagnosing arsenic intoxication using 24-hour urine specimens
Testing Algorithm
Total arsenic will be performed first. If the total arsenic concentration is 10 mcg/L or greater, then speciation will be performed and reported. If total arsenic is below 10 mcg/L, total arsenic will be reported as less than 10 mcg/L and speciation will not be performed.
Special Instructions
Reporting Name
Arsenic Speciation, 24 Hr, USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 28 days |
Frozen | 28 days | |
Ambient | 72 hours |
Reference Values
TOXIC ARSENIC
<35 mcg/L
Reference values apply to all ages.
Arsenic Speciation Interpretive Information:
The toxic arsenic concentration represents the sum of the inorganic and methylated arsenic species. The reference value for toxic arsenic is <35 mcg/L. This value is based on the American Conference of Governmental Industrial Hygienists (ACGIH) Biological Exposure Index (BEI), which does not include the non-toxic organic arsenic.
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82175
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
SPASU | Arsenic Speciation, 24 Hr, U | 96253-0 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
609384 | Inorganic Arsenic (Toxic) | 41992-9 |
609385 | Methylated Arsenic (Toxic) | 96252-2 |
609386 | Organic Arsenic (Non-Toxic) | 43181-7 |
609406 | Toxic Arsenic Concentration | 96251-4 |
609387 | Total Arsenic Concentration | 21074-0 |