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HelpTest ID SSCP Systemic Sclerosis Criteria Panel, Serum
Method Name
NAIFA: Indirect Immunofluorescence
SCL70: Multiplex Flow Immunoassay
RNAP: Enzyme-Linked Immunosorbent Assay (ELISA)
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.7 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reporting Name
Systemic Sclerosis Panel, SSpecimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Report Available
2 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SSCP | Systemic Sclerosis Panel, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SCL70 | Scl 70 Ab, IgG, S | 47322-3 |
| RNAP | RNA Polymerase III Ab, IgG, S | 79182-2 |
| ANAH | Antinuclear Ab, HEp-2 Substrate, S | 59069-5 |
| 1TANA | ANA Titer: | 33253-6 |
| 1PANA | ANA Pattern: | 49311-4 |
| 2TANA | ANA Titer 2: | 33253-6 |
| 2PANA | ANA Pattern 2: | 49311-4 |
| CYTQL | Cytoplasmic Pattern: | 55171-3 |
| LCOM | Lab Comment: | 77202-0 |
Useful For
Evaluating patients with antinuclear antibody-associated connective tissue disease, specifically systemic sclerosis
Day(s) Performed
Tuesday, Thursday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86039
86235
83516
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| NAIFA | Antinuclear Ab, HEp-2 Substrate, S | Yes | Yes |
| SCL70 | Scl 70 Ab, IgG, S | Yes | Yes |
| RNAP | RNA Polymerase III Ab, IgG, S | Yes | Yes |
Specimen Minimum Volume
0.5 mL
Reference Values
ANTINUCLEAR ANTIBODIES, HEp-2 SUBSTRATE, IgG
<1:80 (Negative)
Scl 70 ANTIBODIES, IgG
<1.0 U (negative)
≥ 1.0 U (Positive)
RNA POLYMERASE III ANTIBODIES, IgG
<20.0 U (Negative)
20.0-39.9 U (Weak positive)
40.0-80.0 U (Moderate positive)
>80.0 U (Strong positive)