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Test ID TRCNG Trichinella Antibody, IgG, Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Secondary ID

616733

Useful For

As an adjunct in the diagnosis of trichinosis

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Trichinella Ab, IgG, S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 30 days
  Refrigerated  5 days

Clinical Information

Trichinosis is an infection by the nematode parasite, Trichinella spiralis. The infection is acquired by ingestion of larvae in inadequately cooked, contaminated meat, especially pork, bear, and walrus meat. After ingestion, acid-pepsin digestion in the stomach liberates the larvae, which develop into adult worms in the small intestine. After fertilization, the female worm produces larvae that penetrate the mucosa and seed the skeletal muscles via the blood stream. The larvae coil and encyst in muscle fibers, remaining viable for up to several years.

 

Diarrhea is the most common symptom associated with intestinal infection with adult worms. Fever, periorbital swelling, muscle pain and swelling, pulmonary symptoms, and rash develop during systemic invasion by the larvae.

Reference Values

Negative

Reference values apply to all ages.

Cautions

Antibodies to Trichinella spiralis may not be detectable until 3 weeks after the onset of infection. Therefore, negative results in suspicious cases should be followed by repeat testing in several weeks.

 

Sensitivity of the test may also be affected by the level of invasive disease, with patients who have lower parasitic loads having a greater risk of being negative by the assay.

 

Cross reactions with antibodies against Toxocara canis are possible.

Day(s) Performed

Tuesday, Thursday

Report Available

1 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86784

NY State Approved

Yes