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Test ID UNHB Hemoglobin Stability, Blood


Specimen Required


Only orderable as part of a profile or as a reflex. For more information see:

-HAEV1 / Hemolytic Anemia Evaluation, Blood

-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

-REVE2 / Erythrocytosis Evaluation, Blood

-MEV1 / Methemoglobinemia Evaluation, Blood

 

Container/Tube: Lavender top (EDTA)

Specimen Volume: 4 mL


Secondary ID

9095

Useful For

Work-up of congenital hemolytic anemias

Method Name

Only orderable as part of a profile or as a reflex. For more information see:

-HAEV1 / Hemolytic Anemia Evaluation, Blood

-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

-REVE2 / Erythrocytosis Evaluation, Blood

-MEV1 / Methemoglobinemia Evaluation, Blood

 

Isopropanol and Heat Stability

Reporting Name

Hb Stability, B

Specimen Type

Whole Blood EDTA

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated 7 days

Clinical Information

Unstable hemoglobin disease is rare and may be caused by any one of a large number of hemoglobin variants. They are inherited as autosomal dominant traits. The severity of the disease varies according to the hemoglobin variant; there may be no clinical symptoms, or the disease may produce a mild, moderate, or severe hemolytic anemia.

 

The stained peripheral blood smear shows anisocytosis, poikilocytosis, basophilic stippling, polychromasia and, sometimes, hypochromia. The reticulocyte count may be increased. Splenomegaly and Heinz bodies may also be present.

Reference Values

Only orderable as part of a profile or as a reflex. For more information see:

-HAEV1 / Hemolytic Anemia Evaluation, Blood

-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

-REVE2 / Erythrocytosis Evaluation, Blood

-MEV1 / Methemoglobinemia Evaluation, Blood

 

Normal (reported as normal [stable] or abnormal [unstable])

Cautions

False-positive results will be obtained in blood specimens containing greater than 5% fetal hemoglobin or in specimens greater than 1 week old.

Day(s) Performed

Monday through Friday 

Report Available

1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83068

NY State Approved

Yes