Test ID UOSMU Osmolality, Urine
Useful For
Assessing the concentrating and diluting ability of the kidney
Method Name
Freezing Point Depression
Reporting Name
Osmolality, USpecimen Type
UrineContainer/Tube: Plastic, 10-mL urine tube (Supply T068)
Specimen Volume: 5 mL
Collection Instructions: Collect a random urine specimen.
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 7 days |
Frozen | 7 days |
Clinical Information
Osmolality is an index of the solute concentration. Urine osmolality is a measure of the concentration of osmotically active particles, principally sodium, chloride, potassium, and urea; glucose can contribute significantly to the osmolality when present in substantial amounts in urine. Urinary osmolality corresponds to urine specific gravity in nondisease states.
The ability of the kidney to maintain both tonicity and water balance of the extracellular fluid can be evaluated by measuring the osmolality of the urine either routinely or under artificial conditions. More information concerning the state of renal water handling or abnormalities of urine dilution or concentration can be obtained if urinary osmolality is compared to serum osmolality and if urine electrolyte studies are performed. Normally, the ratio of urine osmolality to serum osmolality is 1.0 to 3.0, reflecting a wide range of urine osmolality.
Reference Values
0-11 months: 50-750 mOsm/kg
≥12 months: 150-1,150 mOsm/kg
Cautions
No significant cautionary statements
Day(s) Performed
Monday through Sunday; Continuously
Report Available
Same day/1 dayPerforming Laboratory

Test Classification
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
83935