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Test ID UOSMU Osmolality, Urine

Useful For

Assessing the concentrating and diluting ability of the kidney

Method Name

Freezing Point Depression

Reporting Name

Osmolality, U

Specimen Type

Urine

Container/Tube: Plastic, 10-mL urine tube (Supply T068)

Specimen Volume: 5 mL

Collection Instructions: Collect a random urine specimen.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Clinical Information

Osmolality is an index of the solute concentration. Urine osmolality is a measure of the concentration of osmotically active particles, principally sodium, chloride, potassium, and urea; glucose can contribute significantly to the osmolality when present in substantial amounts in urine. Urinary osmolality corresponds to urine specific gravity in nondisease states.

 

The ability of the kidney to maintain both tonicity and water balance of the extracellular fluid can be evaluated by measuring the osmolality of the urine either routinely or under artificial conditions. More information concerning the state of renal water handling or abnormalities of urine dilution or concentration can be obtained if urinary osmolality is compared to serum osmolality and if urine electrolyte studies are performed. Normally, the ratio of urine osmolality to serum osmolality is 1.0 to 3.0, reflecting a wide range of urine osmolality.

Reference Values

0-11 months: 50-750 mOsm/kg

≥12 months: 150-1,150 mOsm/kg

Cautions

No significant cautionary statements

Day(s) Performed

Monday through Sunday; Continuously

Report Available

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83935

NY State Approved

Yes