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Test ID URCU Uric Acid, 24 Hour, Urine

Useful For

Assessment and management of patients with kidney stones, particularly uric acid stones

Method Name

Uricase

Reporting Name

Uric Acid, U

Specimen Type

Urine

Container/Tube: Plastic, 5-mL tube (Supply T465)

Specimen Volume: 5 mL

Collection Instructions:

1. Add 10 g of boric acid as preservative at start of collection.

2. Collect urine for 24 hours.

3. Mix well before taking 5-mL aliquot.

Additional Information:

1. 24-Hour volume is required.
2. See Urine Preservatives in Special Instructions for multiple collections.

 

Urine Preservative Collection Options

Ambient

No

Refrigerated

Yes

Frozen

Yes

6N HCl

No

50% Acetic Acid

No

Na2CO3

Yes

Toluene

Yes

6N HNO3

No

Boric Acid

Preferred

Thymol

Yes

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  14 days

Clinical Information

Uric acid is the end-product of purine metabolism. It is freely filtered by the glomeruli and most is reabsorbed by the tubules. There is also active tubular secretion.

 

Increased levels of uric acid in the urine usually accompany increased plasma uric acid levels unless there is a decreased excretion of uric acid by the kidneys. Urine uric acid levels reflect the amount of dietary purines and also endogenous nucleic acid breakdown.

Reference Values

Diet-dependent: <750 mg/24 hours

The reference value is for a 24-hour collection. Specimens collected for other than a 24-hour time period are reported in unit of mg/dL for which reference values are not established.

Cautions

High levels of bilirubin and ascorbic acid may interfere with measurement.

Day(s) Performed

Monday through Sunday; Continuously

Report Available

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84560

NY State Approved

Yes