Test ID URCU Uric Acid, 24 Hour, Urine
Useful For
Assessment and management of patients with kidney stones, particularly uric acid stones
Special Instructions
Method Name
Uricase
Reporting Name
Uric Acid, USpecimen Type
UrineContainer/Tube: Plastic, 5-mL tube (Supply T465)
Specimen Volume: 5 mL
Collection Instructions:
1. Add 10 g of boric acid as preservative at start of collection.
2. Collect urine for 24 hours.
3. Mix well before taking 5-mL aliquot.
Additional Information:
1. 24-Hour volume is required.
2. See Urine
Preservatives in Special Instructions for multiple collections.
Urine Preservative Collection Options
Ambient |
No |
Refrigerated |
Yes |
Frozen |
Yes |
6N HCl |
No |
50% Acetic Acid |
No |
Na2CO3 |
Yes |
Toluene |
Yes |
6N HNO3 |
No |
Boric Acid |
Preferred |
Thymol |
Yes |
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 14 days |
Frozen | 14 days |
Clinical Information
Uric acid is the end-product of purine metabolism. It is freely filtered by the glomeruli and most is reabsorbed by the tubules. There is also active tubular secretion.
Increased levels of uric acid in the urine usually accompany increased plasma uric acid levels unless there is a decreased excretion of uric acid by the kidneys. Urine uric acid levels reflect the amount of dietary purines and also endogenous nucleic acid breakdown.
Reference Values
Diet-dependent: <750 mg/24 hours
The reference value is for a 24-hour collection. Specimens collected for other than a 24-hour time period are reported in unit of mg/dL for which reference values are not established.
Cautions
High levels of bilirubin and ascorbic acid may interfere with measurement.
Day(s) Performed
Monday through Sunday; Continuously
Report Available
Same day/1 dayPerforming Laboratory

Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
84560