Test ID VDSFQ VDRL Titer, Spinal Fluid
Specimen Required
Only orderable as a reflex. For more information see VDSF / VDRL, Spinal Fluid.
Collection Container/Tube: Sterile vial
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Secondary ID
65036Useful For
Aiding in the diagnosis of neurosyphilis
Testing Algorithm
Only orderable as a reflex. For more information see VDSF / VDRL, Spinal Fluid.
Method Name
Only orderable as a reflex. For more information see VDSF / VDRL, Spinal Fluid.
Flocculation/Agglutination
Reporting Name
VDRL Titer, CSFSpecimen Type
CSFSpecimen Minimum Volume
0.2 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
CSF | Frozen (preferred) | 14 days |
Refrigerated | 14 days |
Clinical Information
VDRL is a nontreponemal serologic test for syphilis that uses a cardiolipin-cholesterol-lecithin antigen to detect reaginic antibodies.
The presence of neurosyphilis in untreated patients can be detected by the presence of pleocytosis, elevated protein, and a positive VDRL.
Reference Values
Only orderable as a reflex. For more information see VDSF / VDRL, Spinal Fluid.
Negative
Reference values apply to all ages.
Cautions
VDRL testing on spinal fluid gives a high percentage of false-negative results.
Day(s) Performed
Monday through Friday
Report Available
1 to 3 daysPerforming Laboratory

Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86593