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HelpTest ID VLTUX Volatile Screen, Chain of Custody, Random, Urine
Ordering Guidance
For best clinical correlation, the recommended test is VLTBX / Volatile Screen, Chain of Custody, Blood.
Additional Testing Requirements
If urine creatinine is required or adulteration of the sample is suspected, order ADLTX / Adulterants Survey, Chain of Custody, Random, Urine in addition to this test.
Specimen Required
Supplies: Chain-of-Custody Kit (T282)
Container/Tube: Chain-of-Custody Kit containing the specimen containers, seals, and documentation required.
Specimen Volume: 10 mL
Collection Instructions: Collect a random urine specimen using the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain of custody testing.
Forms
1. Chain of Custody Request is included in the Chain-of-Custody Kit (T282).
2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Secondary ID
62746Useful For
Detecting the presence of acetone, methanol, isopropanol, or ethanol in urine with subsequent quantitation
Providing chain of custody for when the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was always under the control of personnel involved with testing the specimen; this control implies that the opportunity for specimen tampering would be limited.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| COCH | Chain of Custody Processing | No | Yes |
Testing Algorithm
This test includes analysis of methanol, ethanol, isopropanol, and acetone.
Method Name
Headspace Gas Chromatography Flame Ionization Detector (HSGC-FID)
Reporting Name
Volatile Screen, CoC, USpecimen Type
UrineSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 24 hours |
Clinical Information
Urine provides a medium for easy screening for methanol, ethanol, isopropanol, and acetone.
Chain of custody is required whenever the results of testing could be used in a court of law. Chain of custody is a record of the disposition of a specimen to document the individuals that collected it, handled it, and performed the analysis. When a specimen is submitted in this manner, analysis will be performed in such a way that it will withstand regular court scrutiny.
Reference Values
Methanol
Not detected (Positive results are quantitated.)
Cutoff concentration: 10 mg/dL
Toxic concentration: ≥10 mg/dL
Ethanol
Not detected (Positive results are quantitated.)
Cutoff concentration: 10 mg/dL
Isopropanol
Not detected (Positive results are quantitated.)
Cutoff concentration: 10 mg/dL
Toxic concentration: ≥10 mg/dL
Acetone
Not detected (Positive results are quantitated.)
Cutoff concentration: 10 mg/dL
Toxic concentration: ≥10 mg/dL
Cautions
Quantitation of acetone, methanol, isopropanol, or ethanol in urine correlates poorly with degree of intoxication.
Day(s) Performed
Monday through Saturday
Report Available
1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80320
G0480 (if appropriate)